Amiodarone which is used to control irregular heartbeat also has a protective effect in malaria. It triggers eryptosis and the clearance of malaria infected erythrocytes. In Plasmodium berghei infected mice amiodarone injections increased the survival. It is interesting to note that amiodarone is also active against other tropical diseases like Chagas or Leishmaniasis, both in vitro and in vivo, probably by disrupting the parasites' Ca(2+) homeostasis, Bobbala D, Alesutan I, Föller M, Protective effect of amiodarone in malaria. Acta...

After 7 days tea treatment: All parasites are eliminated., no recrudescence, no resistance. No gametocytes left, no transmission: eradication is possible Prophylactic strengthening of the immune system: no reinfection after 27 days

De premiers essais en 2009 menés par IFBV-BELHERB avaient montré que la tisane Artemisia annua et la lumière UV tétanisaient les Paramécies dans l’eau. Ce protozoaire est souvent utilisé pour étudier la présence de substances chimiques dans les milieux aquatiques. Nous avons suggéré à une équipe de jeunes chercheurs katangais, Dr Jérôme Munya et Dr Constant Kansongo de reprendre ces expériences sur base du document en annexe pour voir si des essais sur Paramécie permettraient éventuellement de mieux comprendre l’action...

Vaccines blocking the invasion of malaria sporozoites failed so far, after 30 years of efforts, millions spent, and disastrous human clinical trials. The efforts and the millions are now focused on vaccines blocking transmission by gametocytes. The results are not yet encouraging but the updated Malaria Vaccine Technology Roadmap foresees that there will be a TBV vaccine available in 2030. The update was necessary as the program launched by WHO in 2000 ( TDR/RBM/MAL/VAC/2000.1) has not yet progressed very far. Ogobara K. Doumbo,...

Vaccines blocking the invasion of malaria sporozoites failed so far, after 30 years of efforts, millions spent, and disastrous human clinical trials. The efforts and the millions are now focused on vaccines blocking transmission by gametocytes. The results are not yet encouraging but the updated Malaria Vaccine Technology Roadmap foresees that there will be a TBV vaccine available in 2030. The update was necessary as the program launched by WHO in 2000 ( TDR/RBM/MAL/VAC/2000.1) has not yet progressed very far. Ogobara K. Doumbo, Karamoko...